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93 Histone modification and chromatin remodelling Recent studies have revealed a characteristic histone acetylation signature in the brains of ASD patients, providing strong evidence that histone modifications, especially acetylation, lead to ASD-like behaviours

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Epigenetically, folate supports DNA methylation critical for embryonic gene expression, with deficiencies linked to hyperhomocysteinemia and developmental defects in animal models

[DOI] [PubMed] [Google Scholar] 303.Wang Q., Ying Q., Zhu W., Chen J