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Constans, T., Bacq, Y, Brechot, J.-E, Guilmot, J.-L., Choutet, P

Intriguingly, when older mice were given MOTS-c injections to restore their MOTS-c to more youthful levels, it reversed certain aging effects specifically, it restored insulin sensitivity in aged muscles and improved the animals exercise capacity to levels comparable with younger mice

Unknown long-term consequences

Other key findings about the challenges of dementia caregiving Caregivers of people living with Alzheimer's or other dementias are twice as likely as caregivers of individuals without dementia (22% compared with 11%) to report that completing medical or nursingrelated tasks (for example, injections, tube feedings and catheter or colostomy care) was difficult

10.1016/j.pharmthera.2019.05.010 55 WangQ.YuS.SimonyiA.RottinghausG.SunG

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