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Metsera took a slightly different approach, but like everyone else in the GLP-1 space found out that actually slow titration is better

The ability to return to activities abandoned due to chronic pain, improved quality of life, and sustained relief rather than temporary symptom reduction characterize successful long-term protocols

"Pentadecapeptide BPC 157 and the central nervous system." Neural Regeneration Research 17.3(2022):6

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