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179 Ass-deficient prostate and pancreatic cancers have also been shown to be sensitive to ADI-PEG20, and ADI-PEG20 promotes cell death by inducing autophagy and apoptosis

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They interfere with immune cell function and can alter cytokine production, disrupting the bodys ability to mount an effective immune response

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Blood 107: 29432951, 2006 [DOI] [PubMed] [Google Scholar] 100.Klings ES