Specifically, a few ingredients with low OB or DL were chosen as candidate ingredients because of their high bioactivity according to the literature
Historically the use of copper ionophores such as PBT2 have failed to produce efficacious results in clinical trials (Summers et al., 2022), but crucially they have been investigated without the addition of copper, probably due to the theory that it was primarily to disaggregate copper loaded plaques, in which case PBT2 would act as a chelator (Drew, 2017)
Reduced oxidative stress is another perk, as controlling free radicals ensures your body functions smoothly without additional stressors
Ultimately, an anti-inflammatory diet based on eliminating sugar and refined foods, along with your particular food sensitivities, where you digest your food easily, support your liver, and feed your estrobolome is your best bet
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In summary, two main mechanisms of action of garlic organosulfur compounds emerged from the reported studies: (1) the reaction of garlic compounds to the free sulfhydryl group on the proteins and/or enzymes to inactivate them, and (2) the disruption of composition and integrity of bacterial cell membrane and/or cell wall
