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Using structural equation models (SEMs) the mutual and overlapping influences of mitochondrial respiration and prenatal PM 2.5 exposure on both neurodevelopment and behavior is demonstrated in individuals with ASD

These include intranasal administration, which allows NGF to bypass the BBB and reach brain parenchyma, and the development of NGF-mimetic small molecules or selective TrkA agonists (Rogdakis et al., 2022