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Biodistribution of Lf-cyanine 5.5 (Cy5.5)-LPs BALB/c nude mice were assigned to four groups (10 mice/group) and intravenously injected with saline, free Cy5.5, Cy5.5-loaded LPs (Cy5.5-LPs), or Lf-Cy5.5-LPs
doi: 10.1038/nature17041 68 LimaNCRMeloTQSakugawaAYSMeloKPFerrariMFR
This means: No human PK reference data No human bioavailability data No human metabolism or clearance data Rodent-to-human PK extrapolation is therefore speculative This is a major context for research framing
BPC-157 side effects are relatively uncommon, but may include nausea, diarrhea, and dizziness
High plasma coenzyme Q10 concentration is correlated with good left ventricular performance after primary angioplasty in patients with acute myocardial infarction