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This typically becomes noticeable 2 to 3 weeks after the final dose, when circulating retatrutide levels have dropped below the therapeutic threshold

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Your Brain Needs Water to Perform Water helps your brain: Deliver oxygen and nutrients to brain cells Remove waste products Maintain healthy blood flow Support communication between nerve cells Regulate body temperature Maintain normal electrolyte balance When you're dehydrated, your brain has to work harder to accomplish everyday tasks, leaving you feeling mentally drained

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Eat smaller meals during week 1