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The reduced expression of pykF in MG12345 led to an increase in the intracellular concentration of PEP and also caused an increase in the concentrations of G6P and F6P, which in turn decreased the glucose uptake rate

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consequently, the total body levels do not completely express the bodys VitD stores ( Lastly, it is the active metabolites of VitD that play a significant role in this microbiome interaction

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