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Preclinical studies using transgenic models consistently report improvements in cognition and neuropathology, and early clinical trials with peptide-based compounds have provided encouraging, albeit preliminary, results

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Increased levels of GSTP1 expression can also be indicative for enhanced detoxification activity due to xeno- or endo-biotic exposure implicating oxidative stress (Kanwal et al., 2014)

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ATF4 plays a vital role in managing endoplasmic reticulum (ER) stress and oxidative stress

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