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Leung T, Nieto N

The nrf2 pathway in liver diseases

TRAP-1 supports tumor growth by promoting glycolysis, inhibiting succinate dehydrogenase, and activating cytochrome-c oxidase, 234,235,236 although reduced TRAP-1 expression at later stages has been linked to enhanced motility and invasion, suggesting context-dependent roles

By stabilizing A in a soluble, non-aggregated form, these chaperones limit the formation of toxic oligomers and extracellular plaques, which are hallmark pathological features of AD

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