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However, a huge amount directly injected into the blood via injection can result in adverse effects like hypopigmented patches, melanoma, reduction of liver glutathione levels, and lightening of the hair colour

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However, like any medical treatment, there can be some side effects, such as mild discomfort at the injection site, allergic reactions, or gastrointestinal issues

May support healthy aging by preserving metabolic function, maintaining muscle oxidative capacity, and promoting cellular resilience

These processes require balanced hormone levels for proper function

For example, chondrocytes isolated from OA cartilage displayed significant senescence levels, and ABT263 treatment reduced the expression of inflammatory cytokines and promoted cartilage matrix aggregation in OA chondrocytes (Yang et al., 2020)