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This creates a vicious cycle where oxidative stress and neuroinflammation feed into each other, accelerating BBB disruption and neurodegeneration [86,114]

In summary, although this study presents senotherapy as a promising alternative for enhancing anticancer strategies, numerous aspects of its application necessitate further investigation

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Data were analyzed by one-way analysis of variance (ANOVA) test, followed by Bonferronis and Tukeys post hoc test

Dose ranges for different goals The KLOW dosing literature suggests a range from approximately 2.7mg to 8mg total peptide daily, depending on goals and individual response