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*Compounded drugs are permitted to be prescribed under federal law but are not FDA-approved and do not undergo FDA review for safety, effectiveness, or quality

Options include: Isotretinoin (Accutane) - Most effective for severe/cystic acne Hormonal treatments - Spironolactone, birth control (for hormonal acne) Topical retinoids - Tretinoin, adapalene (for mild-moderate acne) Professional treatments - Chemical peels, laser therapy Whatever works for YOUR acne

M.XiongY.SongX.HussainN.ZhuQ.et al (2021)

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IFN- and TNF- producing Th1 cells and cytotoxic CD8+ cells are predominant while levels of IL-10 are low, leading to exacerbated inflammation and tissue destruction ( Figure 6 ) (210)

Administration decisions are clinician-guided