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p21 is required for dextrose-mediated inhibition of mouse liver regeneration

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MOTs-C MOTs-C is a naturally occurring mitochondrial peptide that has drawn significant research interest for its role in cellular energy regulation, insulin sensitivity, and metabolic health

518 The activation of thyroid hormone receptors subsequently stimulates mitogenesis and hepatocyte proliferation by modulating the Wnt/-catenin pathway, both in the normal liver and in the remnant liver after resection

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Clinical data shows MOTS-c improves insulin sensitivity by 3040%, while 5-Amino-1MQ increases energy expenditure by 9% in preclinical modelscombined effects exceed monotherapy outcomes