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Deficiency in this vitamin can lead to loss of neurons, loss of bone density, and birth defects (when in early pregnancy)

People with Lebers hereditary optic neuropathy, a rare inherited optic nerve disorder, may be at risk of severe optic nerve damage with cyanocobalamin

While severe B12 deficiency is relatively uncommon in many developed regions, marginal levels are still frequently observed in older adults, as well as in vegans, vegetarians, and individuals with absorption disorders

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The benefits of a single B12 shot usually last about one to two weeks