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Type 2 diabetes lowers weight loss by about one-third at the same dose: a diabetes trial produced about 10% loss at 2.4 mg versus 15% in non-diabetic obesity

J Acad Nutr Diet

One mechanism involves reducing transforming growth factor beta-1 secretion in fibroblasts

Most side effects are minor and manageable, and the biggest risks often come from using low-quality products or going it alone without a proper plan

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