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Inhibition of Thioredoxin/Thioredoxin Reductase Induces Synthetic Lethality in Lung Cancers with Compromised Glutathione Homeostasis

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Glutathione has no direct effect on mTOR signaling, hormone-sensitive lipase, or any pathway involved in body recomposition

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A master mix of the working reagent (WR), sufficient for all samples and standards, was prepared (105 L 1X assay buffer, 1 L GR enzyme, 0.25 L NADPH and 0.5 L DTNB per reaction)

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These 16S rRNA gene reference sequences of the SFB clade are here referred to as host-SFB-geographic origin of host (Supplementary Fig

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We found that K29Ub2-modified OTUD5 was further conjugated with K48-linked ubiquitin chains by UBR5 more efficiently than wild-type OTUD5 (Fig

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