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404,405 In particular, reduced renal excretion leads to abnormal plasma adipokines levels including leptin and adiponectin in CKD patients

It exists in almost every cell of the human body, acting as a primary shield against oxidative stress

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In vitro assessments of cytotoxicity and cellular uptake revealed the efficient release of DOX in hypoxia environments upon azo bond cleavage, leading to higher cytotoxicity than in normal conditions