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GSTs catalyse the reaction of JS-K or PABA/NO with GSH to form a diazeniumdiolate anion that spontaneously decomposes, producing two equivalents of NO (Fig

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3A) (Wu et al

JNK, c-Jun N-terminal kinases

) to form peroxynitrite (ONOO - ) with a rate constant that is larger than that for the SOD-catalyzed dismutation of ( Following NO/ONOO - exposure, significant effects on cellular GSH metabolism are reported

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