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Citation: Raun, K., Hansen, B

Epidermal Growth Factor (EGF): The Epidermal Growth Factor is linked with stimulating the growth of collagen and elastin fibers

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The combination therapy showed promising antitumor efficacy, particularly in models with elevated HIF-1 and TGF- levels, suggesting that simultaneous inhibition of EGFR, VEGF, and hypoxia-related pathways can synergistically suppress tumor progression and may represent a viable strategy for treating resistant EGFR-mutant NSCLC (228)

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