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25 Folate Duration of therapy Patients with pernicious anemia require lifelong therapy, while patients with malabsorption require treatment until underlying condition or diet is corrected

It represents a precautionary approach given limited long-term data rather than a response to documented concerns

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Chondroprotective potential of AOD9604 in cartilage degradation models. Arthritis Res Ther

J Clin Endocrinol Metab 86 : 58135818 Zick Y (2004) Uncoupling insulin signalling by serine/threonine phosphorylation: a molecular basis for insulin resistance

Why trials are inconclusive for weight Many studies mix populations, use different doses, or add other supplements