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Instead of protecting the body, it begins to see the parietal cells of the stomach as a threat

CNS and Neurological Disorders-Drug Targets-CNS and Neurological Disord

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The most cited concern is the same as for GH therapy: IGF-1 elevation has a complex relationship with cancer risk in epidemiological studies, with some analyses suggesting higher IGF-1 correlates with increased risk of certain cancers, while others find the opposite in older populations where IGF-1 is already low [16]

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Elevated renal iron levels promote ALOX activation and oxidative stress