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Ferroptosis is now commonly accepted as a non-redundant contributor to the degeneration of ocular structural cells, with RPE cells and RGCs being the most well-characterized targets
Experimental evidence from diabetic animal models and human kidney tubular epithelial cells exposed to hyperglycemic conditions demonstrates hallmark features of ferroptosis, including mitochondrial shrinkage and disrupted redox homeostasis (122, 125, 126)
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At Allure Medspa, treatment is doctor-led: your skin type, goals, medical history and the most appropriate route (oral, topical or IV) are assessed before any plan is recommended
Reproduced from Kaneto et al (2021), an open source publication ( Indications: a FIRST LINE drug in the treatment of type II diabetes ( except when contraindicated - see below) Metformin has been in use for over 50 yrs, and remains the most commonly prescribed oral hypoglycemic (DeFronzo & Goodman, 1995
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