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Adding Gln to the diet can stimulate arginase activity, causing a conversion of ammonia to the less toxic urea and helping in clearing ammonia from the cells by stimulating its excretion 23,42

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Concurrently, oxidative stress markers (ROS and MDA) are elevated, mitochondrial dynamics are imbalanced (impaired fusion and excessive fission), and antioxidant capacity declines, exacerbating oxidative stress (114)

10.1016/j.neuron.2011.05.001 Neuron 125 MirzadehZ.MerkleF

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As a water-based treatment, the serum needs direct skin contact for optimal absorption