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Since it is known that the sugar levels and the renal function affect the oxidative stress, the correlation between the sugar levels and the renal function and the oxidative stress parameters at T=0 (prior to the intervention) was investigated: the percentage of diabetic patients and the percentage of patients with impaired renal function was similar in the group of patients with normal oxidative stress values and in the group with high values

Importantly, this regulation is context-dependent

Mol Pharmacol 36: 2228

While typically associated with oxidative stress conditions, glutathionylation also occurs under basal physiological conditions, especially during the regulation or regeneration of thiol-containing enzymes like peroxidases

Focal adhesion kinase (FAK) acts as a cellular anchor and signaling hub

See Figure 6 [46]