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, Expression of Abcc1 , which encodes MRP1 that is responsible for extracellular glutathione efflux (Figure 1E), also increased after IRI (Figure 3M)

Phase 2 trial results (48 weeks, adults with obesity): 1 mg dose: 7.2% body weight loss 4 mg dose: 12.9% body weight loss 8 mg dose: 17.3% body weight loss 12 mg dose: 24.2% body weight loss Placebo: 1.6% body weight loss Phase 3 TRIUMPH-4 results: 9 mg dose: 20.0% body weight loss (22.9 kg / 50.5 lbs) 12 mg dose: 23.7% body weight loss (27.2 kg / 60.0 lbs) Placebo: 4.6% body weight loss In a separate phase 3 analysis, retatrutide at the highest dose achieved up to 28.7% weight loss

There are also natural sources of glutathione found in foods such as egg shells and whey protein

Zinc in particular is essential for the activity of natural killer cells and Th17 lymphocytes the immune cells responsible for frontline mucosal defence against fungi

Enhances hydration and smooth skin texture