It bypasses first-pass hepatic metabolism which oral delivery does not allowing a greater proportion of the absorbed peptide to remain intact as it enters circulation.7 The olfactory pathway also provides a potential direct nose-to-brain route, bypassing the blood-brain barrier a property that has generated interest for neuropeptides and potential neurological applications
Along the way the two cover the range of peptides people actually ask about, how to separate credible science from marketing hype, and why "it didn't work for me" almost never means what people think it means
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DOI: 10.1111/andr.70003 HCG vs Related HPG Axis Research Tools HCGs unique combination of high LHCGR affinity, extended half-life, distinct biased agonism profile versus LH, and rich biology spanning gonadal steroidogenesis, fetal development, and trophoblast invasion makes it one of the most versatile and irreplaceable tools in reproductive biology and gonadotropin research