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These include: Age and overall health status Severity of Vitamin B12 deficiency Presence of underlying medical conditions, such as gastrointestinal disorders Concurrent medications that may interact with Vitamin B12 For example, older adults or those with severe deficiencies might need more

Authors reported small statistically significant differences in weekly weight loss at the 1 mg dose with a non-linear dose response, but the abstract data has not been published in full peer-reviewed form

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