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Potential side effects include hives and allergic reactions

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This multi-use stability is the critical practical advantage over single-use sterile water, which carries increasing contamination risk after the first access and cannot reliably support multi-aliquot reconstitution protocols

Off-label veterinary use and animal studies indicate that it is in general well tolerated, although it is not FDA approved for dogs , and should only be used under veterinary supervision

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Recent experimental evidence from Arabidopsis supports the involvement of GLR-mediated signalling in mitochondrial redox imbalance