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Improvements tend to be gradual and work synergistically with other healthy lifestyle practices

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Ferroptosis can contribute to the manifestations of RILI, with IR inducing mitochondrial shrinkage, iron accumulation, ROS, and lipid peroxidation generation, and expression of ferroptosis-related genes [56, 71, 73]

Highly activated NRF2 target genes, encoding detoxification and antioxidant enzymes, confer a great advantage to cancer cells for survival against anti-cancer drugs and irradiation (Wang et al., 2008b