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10.3892/ijo.2020.5116 55 KhorsandiK.KianmehrZ.HosseinmardiZ.HosseinzadehR

On the active site thiol of -glutamylcysteine synthetase: Relationships to catalysis, inhibition, and regulation

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rs1800668 Linked with lower enzyme activity and increased cardiovascular risk in some populations

72 These findings suggest that subnormal ALP levels may be a useful diagnostic tool for HPP, that PLP levels may be useful in patients with a suspected diagnosis of HPP, for screening family members to detect possible heterozygotes, and to monitor response to therapy

Le glutathion rduit ( GSH : G pour le glutathion et SH pour le groupe thiol libre) a un rle important dans la protection cellulaire car il pige des espces ractives de loxygne (ERO) et a une action sur la rduction du peroxyde dhydrogne