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A third widely-cited paper (McCoy 2013, PMID 23055539) the source of the often-repeated "seven orders of magnitude more potent than BDNF" line carries a 2021 Expression of Concern

And from there, I really realized, gosh, these are so cool

Water retention represents a common example

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Ear infections: Ear infections are often a result of allergy, but can also be due to bacterial, fungal, or parasitic infection

These changes lead to the accumulation of damaged proteins in myocytes, thereby reducing their ability to adapt to physiological stress and increasing the risk of heart disease in old age