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Methods: We performed a post-hoc analysis using data of the Third International Stroke Trial (IST-3)

[DOI] [PubMed] [Google Scholar] Navrot N, Gelhaye E, Jacquot JP, Rouhier N

(2007) investigated Epitalon in elderly subjects and observed changes in melatonin rhythms and circadian parameters, establishing the pineal component of the peptides activity profile [2]

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3.3 Clinical relevance, dose, formulation, safety, and interactions of Hydroxytyrosol Human supplementation studies typically use daily HTY doses ranging from approximately 5 to 15 mg, either as purified preparations or within high-phenolic extra virgin olive oil