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FIGURE 4 3.5 FOXO4-DRI inhibits FOXO4-P53 binding and promotes P53 phosphorylation To further elucidate the specific mechanism of FOXO4-DRI in anti-aging, we induced senescence in endothelial cells under OGD conditions and treated these cells either PBS or FOXO4-DRI

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Glutathione and Oxidative Stress Markers Glutathione is a central antioxidant involved in Phase II liver detoxification and cellular protection, as reviewed by Wu et al

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Anselmo AC, Mitragotri S (2019) Nanoparticles in the clinic: An update