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Mean age, baseline BMI and percentage of female participants were considered as the potential effect modifiers (online Supplementary Figures 13)

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Overactive somatostatin (Sst) interneurons caused the continuous de-inhibition of layer 5 pyramidal neurons (L5-PN) in TDP-43 A315T mice and significant reductions in miniature and evoked inhibitory postsynaptic currents

In the complex work-up, treatment and management of growth disorders a thorough understanding of the normal physiology of the axis is essential in taking the right actions (130, 131)