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GSH-dependent glyoxalase 1 and 2 mediate the detoxification of 2-oxoaldehydes, such as methylglyoxal, which is an electrophilic by-product of glycolysis that reacts spontaneously with proteins, lipids, and nucleic acids, causing irreversible damage [139]

are inventors on a patent application for Nb1_gbHSV and Nb2_gbHSV (application number: EP25159392.7)