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DOX increased nitrotyrosine abundance by 68% compared to controls, reflecting heightened oxidative stress

Biphasic activation of apoptosis signal-regulating kinase 1-stress-activated protein kinase 1-c-Jun N-terminal protein kinase pathway is selectively mediated by Ca2 + -permeable -amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors involving oxidative stress following brain ischemia in rat hippocampus

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Afr J Tradit Complement Altern Med 13(5):160169 Kukreja RC, Salloum F, Das A, Ockaili R, Yin C, Bremer YA, Fisher PW, Wittkamp M, Hawkins J, Chou E (2005) Pharmacological preconditioning with sildenafil: basic mechanisms and clinical implications

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95% CI 1.092.26