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As the core PAS sequences were apparently not sufficient to explain the specificity of ICP27-induced transcription termination, we asked if sequences upstream of the PAS (UPS) could determine such specificity

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In addition, activated B cells in RA patient peripheral blood drive inflammatory T helper cell activation and cytokine production via the ICOS-ICOSL pathway, while concomitantly upregulating T cell Glut1 expression to enhance glucose uptake (155)