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These dietary agents may help to suppress the transformative, hyper proliferative and inflammatory processes that initiate carcinogenesis

Specifically, the increased loss of RBCs leads to the increased formation of bilirubin, which further triggers eryptosis by enhancing both Ca 2+ influx, SMase activation, and ceramide production, thus creating a vicious cycle

The correct approach: Test serum B12, MMA, and homocysteine not just serum B12 Use the functional cutoff of 500 pg/mL for optimal status, not the labs lower limit of 200 pg/mL Identify the cause diet, malabsorption, medication, or autoimmune Match the supplementation protocol to the cause and severity Retest to confirm response, and continue monitoring if the underlying cause persists If youre over 50, vegan, taking metformin or PPIs, or experiencing unexplained fatigue, brain fog, or neuropathy get tested

doi: 10.1021/jf00057a004 62 GermainEAugerJGiniesCSiessMHTeyssierC

319 Oxidation of a conserved Cys pair in the MBL changes the protein conformation allowing transcriptional derepression and/or activation of the expression of a genes encoding alcohol dehydrogenase family enzymes