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[PubMed ID: 27374114]

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Published articles that addressed the review objective were discussed and reviewed, and selected papers were supplemented by the clinical experience of the panel

Our review show that although serum homocysteine and cystathione levels are not significantly different in children with autism spectrum disorders compared to those without, serum cysteine is significantly lower in autistic disorder (Figures 4, 5 and 6) which supports the assertion that cysteine production may be the rate limiting step in glutathione synthesis [3134]

Protopapas N, Hamilton LE, Warkentin R et al (2019) The perforatorium and postacrosomal sheath of rat spermatozoa share common developmental origins and protein constituents