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[DOI] [PubMed] [Google Scholar] Petejova N, Martinek A, 2014

Moreover, diary intake of serine can facilitate YAP- and TAZ-driven glutamine and serine catabolism to sustain proline and glycine anabolism and promote collagen biosynthesis, which improves cardiovascular function in PAH rodent models ( Figure 3d )

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doi:10.1007/s00702-021-02306-2

As a result, TIME is formed as a key component of TME, bridging the interplay between tumor cells and immune cells, which is crucial for HCC development and somehow dictates the immunotherapy outcomes

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