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In vitro studies confirm minimal cytotoxicity with no impact on cell viability up to 100 M concentrations across multiple cell types, though higher concentrations may produce non-specific effects that could confound experimental results

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Enwonwu CO, Sanders C

(ii) cytokine storm-induced immune-metabolic reprogramming, which could elevate kynurenine:tryptophan ratio and trigger chronic depression syndrome 729

One key frontier involves personalized nanotherapeutics that account for individual microbiome compositions, immune profiles, and wound pathophysiology

To evaluate the inflammatory cytokine levels in atherosclerotic plaques, mouse plaque tissues in different treatment groups were collected and processed for both ELISA and PCR analysis