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This clean safety profile is what distinguishes this stack from other combination approaches that carry interaction risks

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Nat Rev Genet 8 : 253262

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This frequency can keep B12 levels in the blood within an adequate range for those who cannot absorb Vitamin B12 through diet or supplements

(There is a method, advocated by some US doctors, in which phenobarbitone, a long-acting barbiturate, is substituted for a benzodiazepine and then slowly withdrawn, but this method has no particular advantages over tapering directly from a long-acting benzodiazepine)