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Human pluripotent stem-cell-derived cortical neurons integrate functionally into the lesioned adult murine visual cortex in an area-specific way

Mirror progress is still subtle

Using in situ rat brain perfusion, Qaiser et al

In the AD field, a number of models have been generated based on human mutations and phenotypes in an attempt to recapitulate the disease, mostly in mice

Uma das explicaes para isso seria a de que um organismo saudvel j possui estoques suficientes de L-carnitina nos msculos e, diante de doses extras, o corpo faz uma autorregulao, reduzindo a produo de L-carnitina e priorizando a sntese de outras substncias

Parameters studied were feed consumption, body weight gain, fecal corticosteroids, locomotion and rearing