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10.1111/jnc.13425 J
Huppke P, Weissbach S, Church JA, Schnur R, Krusen M, Dreha-Kulaczewski S, et al
Tolerized macrophages fail to deposit active histone marks (e.g., H3K4me1, H3K27ac) at the promoters of tolerant genes, resembling the immune paralysis seen in sepsis, interestingly, -glucan injection can reverse LPS-induced tolerance by restoring H3K27ac deposition and reactivating macrophage function
dilution, 1:2,000) were purchased from Abcam (Cambridge, MA, USA)
