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Mechanisms controlling cellular and systemic iron homeostasis

Vitamin E, ascorbate, glutathione, glutathione disulfide, and enzymes of glutathione metabolism in cultures of chick astrocytes and neurons: evidence that astrocytes play an important role in antioxidative processes in the brain

We propose that the seemingly opposing roles of GSH in cell survival and cell death reflect the spatial, metabolic, and microenvironmental context in which GSH homeostasis is disrupted

Secondly, system X c , an antiporter of two catalytic subunits, is always utilized for transporting cystine into cells for GSH synthesis

Yet few people realize that its levels naturally decline with age, stress and poor nutrition

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