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The germline EGFR T790M mutation was identified in 2005 among a family of European descent with several members across multiple generations developing LUAD 193

Successive RMP solutions may exhibit large oscillations in their dual multipliers, leading to tailing off and slow convergence (Lbbecke and Desrosiers 2005, Rousseau et al

Molecular biology advances in the 1990s decoded selenocysteine incorporation, a breakthrough in protein synthesis

95% CI, -6.7 to -4.3

Rather than acting through a single pathway, amylin appears to function as part of an integrated physiological system that contributes to nutrient sensing and energy regulation