The discovery that NNMT expression is dramatically elevated in adipose tissue of obese humans and animal models, and that NNMT inhibition or knockdown prevents diet-induced obesity and improves metabolic health, has catalyzed intense research interest in NNMT as a therapeutic target for obesity, metabolic syndrome, and related conditions
[Google Scholar] 88.Natarajan R, Ghosh S, Grogan W
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Myers, a physician residing in Baltimore, developed a program of injecting vitamins and minerals intravenously for various medical conditions
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Recent discoveries suggest that NNMT may play important roles in tissue-specific metabolic regulation beyond its established functions in liver and adipose tissue, including potential roles in brain metabolism, immune cell function, and tissue repair processes