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Visible body composition changes typically emerge around week 3-4, with significant fat loss and waist circumference reduction becoming apparent by weeks 5-8

10.1016/s0928-4257(97)89480-6 102 SelyeH.SzaboS

For a plain-English primer on why Tesamorelin specifically is studied for deep abdominal fat, see our overview of Tesamorelins visceral-fat benefits and safety

The GH component begins to complement TRTs anabolic effects

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